The Analytical Balance for the Development of Treatments against Vaginal Herpes

October 7, 2022by Kalstein

Not all women who are infected with the herpes virus actually get the disease, and so far it is not known exactly why. Visible damage to the lips or genitals may recur in women with the infection. Possible triggers for recurrent genital herpes outbreaks have so far been poorly investigated, but causes may include the following:

  • Permanent psychological stress
  • Exposure to sunlight
  • Colds
  • Physical exertion
  • The tight clothes
  • Skin lesions
  • Menstruation.

Of the two types of virus that cause the disease, genital herpes infection originates from herpes simplex virus type 2, whereas type 1 usually causes cold sores, although there may be exceptions. In any case, treatments with antivirals are recommended in order to prevent the multiplication of the virus, since it has no cure; in the preparation and formulation of these medicines, having instruments such as the analytical balance can be of great help.

How does vaginal herpes disease develop?

Genital herpes pathogens nest in nerve ganglia (ganglia) at the lower end of the spine. From there, they can travel along nerve cords to the skin of the genital area and trigger the rash. The blisters contain a large number of herpes viruses that can be transmitted to other people through direct contact with the skin during sexual intercourse. However, it is very unlikely that you will be infected through towels, bed linen, or toilet seats, to cite a few examples. The possible consequences of the disease are:

  • A yeast fungus infection of the vagina
  • A bladder disorder with problems urinating
  • Rarely, inflammation of the meninges
  • Very rarely, a herpes infection can cause serious skin rashes on the body or affect the eyes

What treatment is used to treat herpes?

Women and usually people who have genital herpes and who take viral (antiviral) drugs are probably slightly less infectious. Medicines containing the active substances acyclovir, famciclovir or valacyclovir may be used. However, the drugs must be taken daily and for a longer period of time. Application as a cream or ointment offers no protection, and it is unclear whether the drugs further reduce the risk of infection if condoms are used anyway.

Antiviral drugs can reduce symptoms and shorten the duration of illness by 2 to 4 days. Treatment of a first outbreak should begin within the first three days; the sooner, the better. Drugs are taken as tablets, and their use differs depending on the active ingredient and dose. Experts recommend the following drugs for treatment of a first flare, which are taken for ten days each:

  • Acyclovir: 200 mg five times daily or 400 mg three times daily,
  • Famciclovir: 250 mg three times daily, or
  • Valacyclovir: 500 mg twice daily.

All three drugs are equally effective. Acyclovir is usually used because it is the most experienced acyclovir. It can also be used intravenously and in creams in the area where the skin rash is. For the preparation or development of these and other herpes medicines, having the appropriate dose of the active ingredient is necessary, in which case, the analytical balance contributes greatly by providing certainty of that data. In general, any procedure for preparing a medicinal product is based on a heavy weight, so having an analytical balance is mandatory

Why use a Kalstein analytical scale for the development of treatments?

Kalstein’s analytical scales are ideal for the development of medicines, as they provide accurate and accurate measurements of the active ingredients and other additives used in the development of treatments for vaginal herpes. With the models YR053501 // YR053502 very small amounts can be weighed, up to a thousandth of a gram with good accuracy; the LCD screen provides a good contrast facilitating the reading of the data, which can also be read in different units of mass such as g, mg and ounces.

To review the information of these scales can be consulted on the manufacturer’s website HERE



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